Dolovich leads a workshop during the Aerosol School in St. Joe\u2019s Campbell Auditorium.<\/strong><\/em>[\/vc_column_text][\/vc_column][vc_column animation_delay=”0″ width=”1\/2″ css=”.vc_custom_1695227624919{margin-left: 20px !important;}”][vc_column_text]<\/p>\nRecognizing the need for basic training in pharmaceutical aerosols, she set to work organizing a course to teach this needed skillset. With faculty composed of Canadian and American aerosol experts from academia and the pharmaceutical industry, the Aerosol School was born.<\/p>\n
The Aerosol School is a three-day teaching program, led by Myrna Dolovich, that offers expert training and information in the field of medical aerosols.<\/p>\n
The course teaches a range of measurements, techniques, and approaches to drug development and inhaler design used in academic and pharmaceutical industry laboratories. The participants also explore clinical applications ranging from the ambulatory settings to critical care.<\/p>\n
From there, says Dolovich, \u201cthey should be able to take the next steps on their own.\u201d<\/p>\n
Now in its eleventh year, the Aerosol school has over 250 students from around the world who have completed the training. By fostering a unique learning environment, Dolovich is helping to ensure that aerosol research in medicine thrives.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=”.vc_custom_1695225374650{padding-right: 24px !important;}”]<\/p>\n
Inhaled Vaccines<\/h3>\n
When the COVID-19 pandemic hit, researchers around the world began working on new vaccines to boost immunity and ultimately save lives. Vaccines can made using new technologies, like mRNA, were seen alongside more common methods, such as viral vector, live attenuated, and inactivated vaccines. There are other variations as well, such as the delivery method \u2013 intra-muscular injection has been common for COVID-19 and many other vaccines, but what if you could deliver a vaccine to where it was needed most?<\/p>\n
[\/vc_column_text][\/vc_column][\/vc_row][vc_row full_width=”stretch_row_content” full_height=”yes” content_placement=”bottom” parallax=”true” parallax_image=”1579″][vc_column][vc_empty_space height=”750″][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css_animation=”slideInRight” css=”.vc_custom_1695321968076{background-color: #ffffff !important;}”]<\/p>\n
Myrna Dolovich in her laboratory at St. Joe\u2019s.<\/strong><\/em><\/p>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<\/p>\n
The respiratory mucosal immune system is the body\u2019s first line of defence for airborne pathogens. Because of this, researchers have been working on methods to deliver vaccines directly into the lungs.<\/p>\n
Prior to the pandemic, researchers at McMaster University, including scientists at the Firestone\u2019s Aerosol Lab, were working on an inhaled vaccine for tuberculosis. They conducted a Phase 1B clinical trial examining the efficacy and safety of a low-dose and high-dose inhaled vaccine, compared to the same vaccine given by intra-muscular injection.<\/p>\n
Dolovich worked to characterize the aerosol device and droplets for the study, which found that a low-dose aerosol vaccine is a superior way to elicit immunity against tuberculosis. Researchers have since demonstrated that other respiratory pathogens, such as COVID-19, have similar benefits when using an inhaled vaccine as compared to an intra-muscular injection.<\/p>\n
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As of November 2022, researchers at McMaster are developing a second-generation COVID-19 inhaled vaccine, with help from clinicians, scientists, and engineers at the Firestone Institute.<\/p>\n
[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_separator][vc_empty_space height=”16″][vc_column_text]<\/p>\n
Whether it\u2019s developing medical devices that improve safety and efficacy of inhaled medications, training the next generation of scientists on the intricacies of aerosol research, or working with partners at McMaster and beyond to develop ground-breaking vaccines for respiratory diseases, the Aerosol Research Laboratory continues to contribute to medical advancements in respirology.<\/p>\n
[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/4″][\/vc_column][vc_column width=”1\/2″][vc_single_image image=”1654″ img_size=”full” alignment=”center”][\/vc_column][vc_column width=”1\/4″][\/vc_column][\/vc_row][vc_row][vc_column][vc_empty_space height=”16″][vc_separator][vc_empty_space][vc_icon icon_fontawesome=”fas fa-book-reader” color=”custom” size=”xl” align=”center” custom_color=”#008b77″ link=”url:%2F2022%2Four-stories%2F|title:Our%20Stories”][vc_column_text]<\/p>\n
Return to Our Stories<\/em><\/a><\/p>\n[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"
[vc_row][vc_column][vc_empty_space height=”24″][vc_empty_space height=”32″][vc_column_text] Aerosol science has been a mainstay of respiratory research at St. Joseph\u2019s Healthcare Hamilton for decades thanks to the work of some incredibly talented clinicians, scientists, and engineers. As the Firestone Institute for Respiratory Health approaches its 45th anniversary, we\u2019re reflecting on some major achievements from the Firestone\u2019s Aerosol Research Laboratory. [\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":893,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-vc.php","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"class_list":["post-399","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/pages\/399","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/comments?post=399"}],"version-history":[{"count":17,"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/pages\/399\/revisions"}],"predecessor-version":[{"id":1759,"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/pages\/399\/revisions\/1759"}],"up":[{"embeddable":true,"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/pages\/893"}],"wp:attachment":[{"href":"https:\/\/reports.rsjh.ca\/2022\/wp-json\/wp\/v2\/media?parent=399"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}